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Pharming Earns Santarus Milestone

BLA planned for Ruconest

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By: Tim Wright

Editor-in-Chief, Contract Pharma

Pharming Group and Santarus have met the primary endpoint in a Phase III study of Ruconest (recombinant human C1 esterase inhibitor) for the treatment of acute attacks of angioedema in patients with Hereditary Angioedema (HAE), triggering a $10 million milestone payment to Pharming. Pharming is eligible to receive an additional $5 million upon FDA acceptance of the BLA for review. The companies expect to submit the BLA for Ruconest in the 1H13.   Sijmen de Vries, Pharming’s chief executive offic...

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